H. Yin, G-I. Lee, and A. D. Hamilton.
Alpha-helix mimetics in drug discovery.
In Z. Huang, editor, Drug Discovery Research in the Post Genomics Era, pages 280-298. John Wiley & Sons, 2007.
E. Stern, J. Klemic, D. Routenberg, P. N. Wyrembak, D. Turner-Evans, A. D. Hamilton, D. A. LaVan, T. Fahmy, and M. A. Reed.
Label-free immunodetection with CMOS-compatible semiconducting nanowires.
Nature 2007, 445, 519-522.
DOI: 10.1038/nature05498
F. L. Delarue, J. Adnane, B. Joshi, M. Blaskovich, D. Wang, J. Hawker, F. Bizouaru, J. Ohkanda, K. Zhu, A. D. Hamilton, S. Chellappan, and S. M. Sebti.
Farnesyltransferase and geranylgeranyltransferase-1 inhibitors upregulate RhoB expression by HDAC1 dissociation, HAT association and histone acetylation of the RhoB promoter.
Oncogene 2007, 26, 633-640.
DOI: 10.1038/sj.onc.1209819
Y. Yin and A. D. Hamilton.
Protein secondary structure mimetics as modulators of protein-protein and protein-ligand interactions.
In S. Schreiber, T. Kapoor, and G. Wess, editors, Chemical Biology, pages 250-269. Wiley-VCH, 2007.
D. M. Tagore, K. I. Sprinz, S. Fletcher, J. Jayawickramarajah, and A. D. Hamilton.
Protein recognition and denaturation by self-assembling fragments on a quadruplex scaffold.
Angewandte Chemie: International Edition 2007, 46, 223-225.
DOI: 10.1002/anie.200603479
A. J. Wilson, J. Hong, S. Fletcher, and A. D. Hamilton.
Recognition of solvent exposed protein surfaces using anthracene derived receptors.
Organic and Biomolecular Chemistry 2007, 5, 276-285.
DOI: 10.1039/B612975G
J. M. Davis, L. K. Tsou, and A. D. Hamilton.
Synthetic non-peptide mimetics of α-helices.
Chemical Society Reviews 2007, 36, 326-334.
DOI: 10.1039/B608043J
J. Becerril, J. Rodriguez, I. Saraogi, and A. D. Hamilton.
Foldamer-based molecular recognition.
In I. Huc and S. Hecht, editors, Foldamers: Structure, Properties, and Applications, pages 195-228. Wiley-VCH, 2007.
D. M. Tagore, K. I; Sprinz, and A. D. Hamilton.
Duplex DNA as a self-assembling template for the identification of bidentate protein-binding agents.
Supramolecular Chemistry 2007, 19, 129-136.
DOI: 10.1080/10610270600990253
I-H. Paik, D. Tapriyal, R. M. Enick, and A. D. Hamilton.
Fiber formation by highly CO2-soluble bis-ureas containing peracylated carbohydrate groups.
Angewandte Chemie, International Edition 2007, 46, 3284-3287.
DOI: 10.1002/anie.200604844
F. Epifano, M. Curini, S. Genovese, M. Blaskovich, A. D. Hamilton, and S. M. Sebti.
Prenyloxyphenylpropanoids as novel lead compounds for the selective inhibition of geranylgeranyltransferase I.
Bioorganic and Medicinal Chemistry Letters 2007, 17, 2639-2642.
DOI: 10.1016/j.bmcl.2007.01.097
S. Fletcher and A. D. Hamilton.
Denaturation and accelerated proteolysis of sizeable heme proteins by synthetic metalloporphyrins.
New Journal of Chemistry 2007, 31, 623-627.
DOI: 10.1039/B700123A
J. Becceril and A. D. Hamilton.
Helix mimetics as inhibitors of the interaction of the estrogen receptor with coactivator peptides.
Angewandte Chemie, International Edition 2007, 46, 4471-4473.
DOI: 10.1002/anie.200700657
S. C. Falsetti, D-A. Wang, H. Peng, D. Carrico, A. D. Cox, C. J. Der, A. D. Hamilton, and S. M. Sebti.
Geranylgeranyltransferase I inhibitors target RalB, to inhibit anchorage-dependent growth and induce apoptosis, and RalA, to inhibit anchorage-independent growth.
Molecular Cell Biology 2007, 27, 8003-8014.
DOI: 10.1128/MCB.00057-07
K. K. Park, J. W. Park, and A. D. Hamilton.
Solvent and pH effects on the fluorescence of 7-(dimethylamino)-2-fluorenesulfonate.
Journal of Fluorescence 2007, 17, 361-369.
DOI: 10.1007/s10895-007-0193-1
J. M. Rodriguez and A. D. Hamilton.
Benzoylurea oligomers: Synthetic foldamers that mimic extended α-helices.
Angewandte Chemie, International Edition 2007, 46, 8614-8617.
DOI: 10.1002/anie.200701869
W. C. Van Voorhis, K. Rivas, P. Bendale, L. Nallan, K. Bauer, C. Horney, L. K. Barrett, S. Ankala, O. Hucke, C. L. M. J. Verlinde, D. Chakrabarti, C. Strickland, K. Yokoyama, F. S. Buckner, A. D. Hamilton, D. K. Williams, L. Lombardo, D. Floyd, and M. H. Gelb.
Tetrahydroquinoline Plasmodium falciparum protein farnesyltransferase inhibitors: Efficacy, pharmacokinetics, mechanism.
Antimicrobial Agents and Chemotherapy 2007, 51, 3659-3671.
DOI: 10.1128/AAC.00246-07
J. Jayawickramarajah, D. M. Tagore, L. K. Tsou, and A. D. Hamilton.
Allosteric control of self-assembly: Modulating guanine quadruplex formation through orthogonal aromatic interactions.
Angewandte Chemie, International Edition 2007, 46, 7583-7586.
DOI: 10.1002/anie.200701883
K. A. Z. Siddiquee, Patrick T. Gunning, M. Glenn, W. P. Katt, S. Zhang, C. Schroeck, S. M. Sebti, R. Jove, A. D. Hamilton, and J. Turkson.
An oxazole-based small-molecular Stat3 inhibitor modulates Stat3 stability and processing and induces antitumor cell effects.
Chemical Biology 2007, 2, 787-798.
DOI: 10.1021/cb7001973
S. Fletcher and A. D. Hamilton.
Protein-protein interaction inhibitors: Small molecules from screening techniques.
Current Topics in Medicinal Chemistry 2007, 7, 922-927.
DOI: 10.2174/156802607780906735
P. T. Gunning, M. Glenn, J. Turkson, J. S. Kim, W. P. Katt, S. M. Sebti, R. Jove, and A. D. Hamilton.
Isoform selective inhibition of STAT1 or STAT3 homodimerization via peptidomimetic probes: Structural recognition of STAT SH2 domains.
Bioorganic and Medicinal Chemistry Letters 2007, 17, 2949-2953.
DOI: 10.1016/j.bmcl.2007.03.063
K. J. Kayser, M. P. Glenn, S. M. Sebti, J. Q. Cheng, and A. D. Hamilton.
Modifications of the GSK3 beta substrate sequence to produce substrate-mimetic inhibitors of Akt as potential anti-cancer therapeutics.
Bioorganic and Medicinal Chemistry Letters 2007, 17, 2068-2073.
DOI: 10.1016/j.bmcl.2007.01.004