H. Peng, D. Carrico, V. Thai, M. A. Blaskovich, C. Bucher, E. E. Pusateri, S. M. Sebti, and A. D. Hamilton.
Synthesis and evaluation of potent, highly-selective, 3-aryl-piperazinone inhibitors of protein geranylgeranyltransferase-I.
Organic and Biomolecular Chemistry 2006, 4(9), 1768-1784.
DOI: 10.1039/B517572K
H. Zhou, L. Baldini, J. Hong, A. J. Wilson, and A. D. Hamilton.
Pattern-recognition of proteins based on an array of functionalized porphyrins.
Journal of the American Chemical Society 2006, 128(7), 2421-2425.
DOI: 10.1021/ja056833c
L. A. Estroff and A. D. Hamilton.
Cryo-TEM, x-ray diffraction and modeling of an organic hydrogel.
In R. Weiss and P. Terech, editors, Molecular Gels, pages 721-42. Springer, 2006.
J. Ohkanda, C. L. Strickland, M. A. Blaskovich, D. Carrico, J. W. Lockman, A. Vogt, C. J. Bucher, J. Sun, Y. Qian, D. Knowles, E. E. Pusateri, S. M. Sebti, and A. D. Hamilton.
Structure-based design of imidazole containing peptidomimetic inhibitors of protein farnesyltransferase.
Organic and Biomolecular Chemistry 2006, 4(3), 482-492.
DOI: 10.1039/B508184J
W. J. Jorgensen, J. Ruiz-Caro, J. Tirado-Rives, A. Basavapathruni, K. S. Anderson, and A. D. Hamilton.
Computer-aided design of non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Bioorganic and Medicinal Chemistry Letters 2006, 16(3), 663-667.
DOI: 10.1016/j.bmcl.2005.10.038
J. Ruiz-Caro, A. Basavapathruni, J. T. Kim, C. M. Bailey, L. Wang, K. S. Anderson, A. D. Hamilton, and W. J. Jorgensen.
Optimization of diarylamines as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Bioorganic and Medicinal Chemistry Letters 2006, 16(3), 668-671.
DOI: 10.1016/j.bmcl.2005.10.037
H. Zhou, D. Wang, L. Baldini, E. Ennis, R. Jain, A. Carie, S. M. Sebti, and A. D. Hamilton.
Structure-activity studies on a library of potent calix[4]arene based PDGF antagonists that inhibit PDGF-stimulated PDGFR tyrosine phosphorylation.
Organic and Biomolecular Chemistry 2006, 4(12), 2376-2386.
DOI: 10.1039/B515483A
I. Kim and A. D. Hamilton.
Diphenylindane-based α-helix proteomimetics as mimics of i, i+3, i+4, and i+7 residues.
Organic Letters 2006, 8(9), 1751-1754.
DOI: 10.1021/ol052956q
S. Fletcher and A. D. Hamilton.
Targeting protein-protein interactions by rational design: Mimicry of protein surfaces
Journal of the Royal Society Interface 2006, 3(7), 215-233.
DOI: 10.1098/rsif.2006.0115
K. K. Park, L. K. Tsou, and A. D. Hamilton.
Facile and selective aerobic oxidation of arylalkanes to aryl ketones using cesium carbonate.
Synthesis 2006, 21, 3617-3620.
DOI: 10.1055/s-2006-950189
M. P. Glenn, S. Y. Chang, O. Hucke, C. Pickeral, K. Rivas, K. Yokoyama, E. Pusateri, S. Fletcher, F. S. Buckner, P. R. Pendyala, C. L. M. J. Verlinde, D. Chakrabarti, M. Gelb, W. C. Van Voorhis, S. M. Sebti, and A. D. Hamilton.
Structurally simple, potent Plasmodium selective farnesyltransferase inhibitors that arrest the growth of malaria parasites.
Journal of Medicinal Chemistry 2006, 49, 5710-5727.
DOI: 10.1021/jm060081v
V. Thakur, J. T. Kim, A. D. Hamilton, C. M. Bailey, R. Domaoal, L. Wang, K. S. Anderson, and W. J. Jorgensen.
Optimization of pyrimidinyl- and triazinylamines as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Bioorganic and Medicinal Chemistry Letters 2006, 16, 5664-5667.
DOI: 10.1016/j.bmcl.2006.08.037
J. M. Rodriguez and A. D. Hamilton.
Intramolecular hydrogen bonding allows simple enaminones to structurally mimic the i, i+4, and i+7 residues of an α-helix.
Tetrahedron Letters 2006, 47, 7443-7446.
DOI: 10.1016/j.tetlet.2006.08.048
J. T. Kim, A. D. Hamilton, C. M. Bailey, R. A. Domoal, L. Wang, K. S. Anderson, and W. L. Jorgensen.
FEP-guided selection of bicyclic heterocycles in lead optimization for non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Journal of the American Chemical Society 2006, 128, 15372-15373.
DOI: 10.1021/ja066472g
A. Anagnostopouloua, R. Arulanandam, J. Cao, J. Turkson, R. Jove, J. S. Kim, M. Glenn, A. D. Hamilton, and Leda Raptis.
Differential effects of Stat3 inhibition in sparse vs confluent normal and breast cancer cells.
Cancer Letters 2006, 242, 120-132.
DOI: 10.1016/j.canlet.2005.10.047
D. Tang, H-J. Park, S. P. Georgescu, S. M. Sebti, A. D. Hamilton, and J. B. Galper.
Simvastatin potentiates tumor necrosis factor alpha-mediated apoptosis of human vascular endothelial cells via the inhibiton of the geranylgeranylation of RhoA.
Life Sciences 2006, 79, 1484-1492.
DOI: 10.1016/j.lfs.2006.04.019