B. P. Orner, X. Salvatella, J. Sanchez Quesada, J. de Mendoza, E. Giralt, and A. D. Hamilton.
De novo protein surface design: Use of cation-π interactions to enhance binding between an α-helical peptide and a cationic molecule in 50% aqueous solution.
Angewandte Chemie International Edition 2002, 41(1), 117-119.
DOI: 10.1002/1521-3773(20020104)41:1<117::AID-ANIE117>3.0.CO;2-J
J. Ohkanda, J. W. Lockman, M. A. Kothare, Y. Qian, M. A. Blaskovich, S. M. Sebti, and A. D. Hamilton.
Design and synthesis of potent non-peptidic farnesyltransferase inhibitors based on a terphenyl scaffold.
Journal of Medicinal Chemistry 2002, 45(1), 177-188.
DOI: 10.1021/jm0103099
R. K. Jain and A. D. Hamilton.
Designing protein denaturants: Synthetic agents induce cytochrome c unfolding at low concentrations and stoichiometries.
Angewandte Chemie: International Edition 2002, 41(4), 641-643.
DOI: 10.1002/1521-3773(20020215)41:4<641::AID-ANIE641>3.0.CO;2-1
A. Zafar, R. Melendez, S. J. Geib, and A. D. Hamilton.
Hydrogen-bond controlled aggregation of guanidinium-carboxylate derivatives in the solid state.
Tetrahedron 2002, 58(4), 683-690.
DOI: 10.1016/S0040-4020(01)01106-1
H. S. Park, Q. Lin, and A. D. Hamilton.
Modulation of protein-protein interactions by synthetic receptors: Design of molecules that disrupt serine protease-proteinaceous inhibitor interaction.
Proceedings of the National Academy of Science 2002, 99(8), 5105-5109.
DOI: 10.1073/pnas.082675899
R. E. Melendez and A. D. Hamilton.
Organogelators: New supramolecular materials.
In A. Biderman, editor, Encyclopedia of Smart Materials, page 472. New York, 2002, Wiley.
G. Wang and A. D. Hamilton.
Synthesis and self-assembling properties of polymerizable organogelators.
Chemistry - A European Journal 2002, 8(8), 1954-1961.
DOI: 10.1002/1521-3765(20020415)8:8<1954::AID-CHEM1954>3.0.CO;2-X
J. Ohkanda, D. B. Knowles, M. A. Blaskovich, S. M. Sebti, and A. D. Hamilton.
Inhibitors of protein farnesyltransferase as novel anticancer agents.
Current Medicinal Chemistry 2002, 2(3), 303-323.
V. K. Potluri, J. Xu, R. Enick, E. Beckman, and A. D. Hamilton.
Peracetylated sugar derivatives show high solubility in liquid and supercritical carbon dioxide.
Organic Letters 2002, 4(14), 2333-2335.
DOI: 10.1021/ol026007y
O. Kutzki, H. S. Park, J. T. Ernst, B. P. Orner, H. Yin, and A. D. Hamilton.
Development of a potent Bcl-xL antagonist based on α-helix mimicry.
Journal of the American Chemical Society 2002, 124(40), 11838-11839.
DOI: 10.1021/ja026861k
Q. Zhao, J. T. Ernst, A. D. Hamilton, and S. Jiang.
XTT formazan widely used to detect cell viability inhibits HIV infection in vitro by inhibiting gp41.
AIDS Research and Human Retroviruses 2002, 18(14), 989-997.
DOI: 10.1089/08892220260235353
A. D. Hamilton.
Chemistry: Much binding in the lab.
Nature 2002, 418(6896), 375-376.
DOI: 10.1038/418375a
Q. Lin and A. D. Hamilton.
Design and synthesis of multiple-loop receptors based on a calix[4]arene scaffold for protein surface recognition.
Comptes Rendues Chimie 2002, 5(5), 441-450.
DOI: 10.1016/S1631-0748(02)01408-X
N. Crespo, F Delarue, D. Carrico, A. D. Hamilton, and S. M. Sebti.
The farnesyltransferase inhibitor, FTI-2153, inhibits mitotic bipolar spindle formation independently of transformation and ras and p53 mutation status.
Cell Death and Differentiation 2002, 9(7), 702-709.
DOI: 10.1038/sj.cdd.4401023
C. E. Walters, G. Pryce, D. J. R. Hankey, A. D. Hamilton, S. M. Sebti, D. Baker, J. Greenwood, and P. Adamson.
Inhibition of Rho GTPases with protein prenyl transferase inhibitors prevent lymphocyte recruitment to the central nervous system and attenuate clinical signs of disease in an animal model of multiple sclerosis.
Journal of Immunology 2002, 168(8), 4087-4094.
X. Liu, J. C. Tupper, D. D. Bannerman, R. K. Winn, S. M. Sebti, A. D. Hamilton, and J. M. Harlan.
Inhibition of protein geranylgeranylation and Rhoa/RhoA kinase pathway induces apoptosis in human endothelial cells.
Journal of Biological Chemistry 2002, 277(18), 15309-15316.
DOI: 10.1074/jbc.M201253200