A. D. Hamilton and S. M. Sebti.
New approaches to anticancer drug design based on the inhibition of farnesyltransferase.
Drug Discovery Today 1998, 3(1), 26-33.
Y. Qian, A. Vogt, A. Vasudevan, S. M. Sebti, and A. D. Hamilton.
Selective inhibition of type-I geranylgeranyltransferase in vitro and in whole cells by CAAL peptidomimetics.
Bioorganic and Medicinal Chemistry 1998, 6(3), 293-299.
DOI: 10.1016/S0968-0896(97)10040-2
A. Zafar, Y. Hamuro, S. J. Geib, and A. D. Hamilton.
New supramolecular arrays based on interactions between carboxylate and urea groups: Solid-state and solution behavior.
New Journal of Chemistry 1998, 22(2), 137-141.
DOI: 10.1039/A707643F
J. Sun, Y. Qian, A. D. Hamilton, and S. M. Sebti.
Both farnesyltransferase and geranylgeranyltransferase 1 inhibitors are required for inhibition of oncogenic K-Ras prenylation but each alone is sufficient to supress human tumor growth in nude mouse xenografts.
Oncogene 1998, 16(11), 1467-1473.
W. S. Weiner and A. D. Hamilton.
Synthesis and binding studies of a 1-alkyl-3,6-diamino-4-quinolone based receptor for N-acylated dipeptides.
Bioorganic and Medicinal Chemistry Letters 1998, 8(6), 681-686.
DOI: 10.1016/S0960-894X(98)00099-7
R. E. Melendez and A. D. Hamilton.
Hydrogen bonded ribbons, tapes and sheets as motifs for crystal engineering.
Topics in Current Chemistry 1998, 198, 97-129.
DOI: 10.1007/3-540-69178-2_3
M. Bredel, I. F. Pollack, J. M. Freund, A. D. Hamilton, and S. M. Sebti.
Inhibition of Ras and related G-proteins as a novel therapeutic strategy for blocking malignant glioma growth.
Neurosurgery 1998, 43(1), 124-131.
W. W. Stark, M. A. Blaskovich, B. A. Johnson, A. Vasudevan, A. D. Hamilton, S. M. Sebti, and P. Davies.
Inhibiting geranylgeranylation blocks growth and promotes apoptosis in pulmonary vascular smooth muscle cells.
American Journal of Physiology: Lung Cellular and Molecular Physiology 1998, 275(1, Pt 1), L55-L63.
Q. Lin, S. J. Geib, and A. D. Hamilton.
1-Phenyl-1H-pyrrole-2,5-dicarboxylic acid derivatives as versatile hydrogen-bonding motifs for the formation of one-, two- and three dimensional networks in the solid state.
Journal of the Chemical Society, Perkin Transactions 2 1998, (10), 2109-2116.
DOI: 10.1039/A803966F
E. Bernhard, W. G. McKenna, A. D. Hamilton, S. M. Sebti, Y. Qian, J. Wu, and R. J. Muschel.
Inhibiting Ras prenylation increases the radiosensitivity of human tumor cell lines with activating mutations of ras oncogenes.
Cancer Research 1998, 58(8), 1754-1761.
A. J. Carr, R. Melendez, S. J. Geib, and A. D. Hamilton.
The design of organic gelators: Solution and solid state properties of a family of bis-ureas.
Tetrahedron Letters 1998, 39(41), 7447-7450.
DOI: 10.1016/S0040-4039(98)01667-0
Y. Shao, B. Linton, A. D. Hamilton, and S. G. Weber.
Electrochemical studies on molecular recognition of anions: Complex formation between xylylenylbis-iminoimidazolinium and dicarboxylates in nitrobenzene and water.
Journal of Electroanalytical Chemistry 1998, 441(1-2), 33-37.
DOI: 10.1016/S0022-0728(97)00394-X
J. Adnane, F. A. Bizouarn1, Y. Qian, A. D. Hamilton, and S. M. Sebti.
p21WAF1/CIP1 is upregulated by the geranylgeranyltransferase I inhibitor GGTI-298 through a transforming growth factor β- Sp1-responsive element: involvement of the small GTPase RhoA.
Molecular and Cellular Biology 1998, 18(12), 6962-6970.
Q. Lin, H. S. Park, Y. Hamuro, C. S. Lee, and A. D. Hamilton.
Protein surface recognition by synthetic agents: Design and structural requirements of a family of artificial receptors that bind to cytochrome c.
Peptide Science 1998, 47(4), 285-297.
DOI: 10.1002/(SICI)1097-0282(1998)47:4<285::AID-BIP4>3.0.CO;2-C
U. Kucich, J. C. Rosenblum, G. Shen, W. R. Abrams, M. A. Blaskovich, A. D. Hamilton, J. Ohkanda, S. M. Sebti, and J. Rosenbloom.
Requirement for geranylgeranyltransferase I and acyltransferase in the TGF-β stimulated pathway leading to elastin mRNA stabilization.
Biochemical and Biophysical Research Communications 1998, 252(1), 111-116.
DOI: 10.1006/bbrc.1998.9544
T. A. Sharma, A. J. Carr, R. S. Davis, I. J. Reynolds, and A. D. Hamilton.
Aromatic analogs of arcaine inhibit MK-801 binding to the NMDA receptor.
Bioorganic and Medicinal Chemistry Letters 1998, 8(24), 3459-3464.
DOI: 10.1016/S0960-894X(98)00631-3
A. P. Sukharevsky, I. Read, B. Linton, A. D. Hamilton, and D. H. Waldeck.
Experimental measurements of low frequency intermolecular host-guest dynamics.
Journal of Physical Chemistry B 1998, 102(27), 5394-5403.
DOI: 10.1021/jp981417i