A. D. Hamilton and S. M. Sebti.
New approaches to anticancer drug design based on the inhibition of farnesyltransferase.
Drug Discovery Today 1998, 3(1), 26-33.
Y. Qian, A. Vogt, A. Vasudevan, S. M. Sebti, and A. D. Hamilton.
Selective inhibition of type-I geranylgeranyltransferase in vitro and in whole cells by CAAL peptidomimetics.
Bioorganic and Medicinal Chemistry 1998, 6(3), 293-299.
A. Zafar, Y. Hamuro, S. J. Geib, and A. D. Hamilton.
New supramolecular arrays based on interactions between carboxylate and urea groups: Solid-state and solution behavior.
New Journal of Chemistry 1998, 22(2), 137-141.
J. Sun, Y. Qian, A. D. Hamilton, and S. M. Sebti.
Both farnesyltransferase and geranylgeranyltransferase 1 inhibitors are required for inhibition of oncogenic K-Ras prenylation but each alone is sufficient to supress human tumor growth in nude mouse xenografts.
Oncogene 1998, 16(11), 1467-1473.
W. S. Weiner and A. D. Hamilton.
Synthesis and binding studies of a 1-alkyl-3,6-diamino-4-quinolone based receptor for N-acylated dipeptides.
Bioorganic and Medicinal Chemistry Letters 1998, 8(6), 681-686.
R. E. Melendez and A. D. Hamilton.
Hydrogen bonded ribbons, tapes and sheets as motifs for crystal engineering.
Topics in Current Chemistry 1998, 198, 97-129.
M. Bredel, I. F. Pollack, J. M. Freund, A. D. Hamilton, and S. M. Sebti.
Inhibition of Ras and related G-proteins as a novel therapeutic strategy for blocking malignant glioma growth.
Neurosurgery 1998, 43(1), 124-131.
W. W. Stark, M. A. Blaskovich, B. A. Johnson, A. Vasudevan, A. D. Hamilton, S. M. Sebti, and P. Davies.
Inhibiting geranylgeranylation blocks growth and promotes apoptosis in pulmonary vascular smooth muscle cells.
American Journal of Physiology: Lung Cellular and Molecular Physiology 1998, 275(1, Pt 1), L55-L63.
Q. Lin, S. J. Geib, and A. D. Hamilton.
1-Phenyl-1H-pyrrole-2,5-dicarboxylic acid derivatives as versatile hydrogen-bonding motifs for the formation of one-, two- and three dimensional networks in the solid state.
Journal of the Chemical Society, Perkin Transactions 2 1998, (10), 2109-2116.
E. Bernhard, W. G. McKenna, A. D. Hamilton, S. M. Sebti, Y. Qian, J. Wu, and R. J. Muschel.
Inhibiting Ras prenylation increases the radiosensitivity of human tumor cell lines with activating mutations of ras oncogenes.
Cancer Research 1998, 58(8), 1754-1761.
A. J. Carr, R. Melendez, S. J. Geib, and A. D. Hamilton.
The design of organic gelators: Solution and solid state properties of a family of bis-ureas.
Tetrahedron Letters 1998, 39(41), 7447-7450.
Y. Shao, B. Linton, A. D. Hamilton, and S. G. Weber.
Electrochemical studies on molecular recognition of anions: Complex formation between xylylenylbis-iminoimidazolinium and dicarboxylates in nitrobenzene and water.
Journal of Electroanalytical Chemistry 1998, 441(1-2), 33-37.
J. Adnane, F. A. Bizouarn1, Y. Qian, A. D. Hamilton, and S. M. Sebti.
p21WAF1/CIP1 is upregulated by the geranylgeranyltransferase I inhibitor GGTI-298 through a transforming growth factor β- Sp1-responsive element: involvement of the small GTPase RhoA.
Molecular and Cellular Biology 1998, 18(12), 6962-6970.
Q. Lin, H. S. Park, Y. Hamuro, C. S. Lee, and A. D. Hamilton.
Protein surface recognition by synthetic agents: Design and structural requirements of a family of artificial receptors that bind to cytochrome c.
Peptide Science 1998, 47(4), 285-297.
U. Kucich, J. C. Rosenblum, G. Shen, W. R. Abrams, M. A. Blaskovich, A. D. Hamilton, J. Ohkanda, S. M. Sebti, and J. Rosenbloom.
Requirement for geranylgeranyltransferase I and acyltransferase in the TGF-β stimulated pathway leading to elastin mRNA stabilization.
Biochemical and Biophysical Research Communications 1998, 252(1), 111-116.
T. A. Sharma, A. J. Carr, R. S. Davis, I. J. Reynolds, and A. D. Hamilton.
Aromatic analogs of arcaine inhibit MK-801 binding to the NMDA receptor.
Bioorganic and Medicinal Chemistry Letters 1998, 8(24), 3459-3464.
A. P. Sukharevsky, I. Read, B. Linton, A. D. Hamilton, and D. H. Waldeck.
Experimental measurements of low frequency intermolecular host-guest dynamics.
Journal of Physical Chemistry B 1998, 102(27), 5394-5403.