E. Fan, C. Vincent, and A. D. Hamilton.
Molecular recognition and catalysis: Incorporation of an "oxyanion hole" into a synthetic receptor.
New Journal of Chemistry 1997, 21(1), 81-85.
J. S. Albert, M. Peczuh, and A. D. Hamilton.
Design, synthesis and evaluation of synthetic receptors for protein functional groups: Recognition of aspartate pairs in α-helical peptides.
Bioorganic and Medicinal Chemistry 1997, 5(8), 1455-1467.
DOI: 10.1016/S0968-0896(97)00086-2
J. D. Finder, J. L. Litz, M. A. Blaskovitch, T. F. McGuire, Y. Qian, A. D. Hamilton, P. Davies, and S. M. Sebti.
Inhibition of protein geranylgeranylation causes a superinduction of nitric oxide synthase by interleukin-β in artery smooth muscle cells.
Journal of Biological Chemistry 1997, 272(21), 13484-13488.
DOI: 10.1074/jbc.272.21.13484
Y. Hamuro, S. J. Geib, and A. D. Hamilton.
Novel folding patterns in a family of oligoanthranilamides: non-peptide oligomers that form extended helical secondary structures.
Journal of the American Chemical Society 1997, 119(44), 10587-10593.
DOI: 10.1021/ja963449u
Y. Qian, S. M. Sebti, and A. D. Hamilton.
Farnesyltransferase as a target for anti-cancer drug design.
Biopolymers 1997, 43(1), 25-41.
DOI: 10.1002/(SICI)1097-0282(1997)43:1<25::AID-BIP4>3.0.CO;2-2
S. M. Sebti and A. D. Hamilton.
Inhibition of ras prenylation: A novel approach to cancer chemotherapy.
Pharmacology and Therapeutics 1997, 74(1), 103-114.
DOI: 10.1016/S0163-7258(97)00014-4
S. Liu and A. D. Hamilton.
Catalysis of phosphodiester transesterification by Cu(II)-terpyridine complexes with peripheral pendent base groups: Implications for the mechanism.
Tetrahedron Letters 1997, 38(7), 1107-1110.
DOI: 10.1016/S0040-4039(96)02519-1
A. Vogt, Y. Qian, A. D. Hamilton, and S. Sebti.
The geranylgeranyltransferase-i inhibitor GGTI-298 arrests human tumor cells in G0/G1 and induces p21WAF1/CIP1/SDI1 in a p53-independent manner.
Journal of Biological Chemistry 1997, 272(43), 27224-27229.
DOI: 10.1074/jbc.272.43.27224
B. Linton and A. D. Hamilton.
Formation of artificial receptors by metal templated self-assembly.
Chemical Reviews 1997, 97(5), 1669-1680.
DOI: 10.1021/cr960375w
G. Das and A. D. Hamilton.
Carbohydrate recognition: Enantioselective spirobifluorene diphosphonate receptors.
Tetrahedron Letters 1997, page 3675.
DOI: 10.1016/S0040-4039(97)00725-9
G. J. Clark, M. S. Kinch, K. Rogers-Graham, S. M. Sebti, A. D. Hamilton, and C. J. Der.
The Ras-related protein Rheb is farnesylated and antagonizes Ras signaling and transformation.
Journal of Biological Chemistry 1997, 272(16), 10608-10615.
DOI: 10.1074/jbc.272.16.10608
E. C. Lemer, A. D. Hamilton, and S. M. Sebti.
Inhibition of ras prenylation.
Anti-Cancer Drug Design 1997, 12, 229.
S. M. Sebti and A. D. Hamilton.
Inhibitors of prenyltransferases.
Current Opinions in Oncology 1997, 9(6), 557-561.
S. Liu and A. D. Hamilton.
Catalysis of phosphodiester transesterification by dinuclear copper(II) complexes: The role of the second Cu(II) ion.
Bioorganic and Medicinal Chemistry Letters 1997, 7(13), 1779-1784.
DOI: 10.1016/S0960-894X(97)00303-X
E. C. Lemer, T. T. Zhang, D. Knowles, Y. Qian, A. D. Hamilton, and S. M. Sebti.
Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resisitant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltranferase I inhibitor in human cell lines.
Oncogene 1997, 15(11), 1283-1288.
Y. Hamuro, M. C. Calama, H. S. Park, and A. D. Hamilton.
A calixarene with four peptide loops: An antibody mimic for recognition of protein surfaces.
Angewandte Chemie International Edition English 1997, 36(23), 2680-2683.
DOI: 10.1002/anie.199726801
B. Linton and A. D. Hamilton.
Self-assembling metal templated receptors.
Chemtech 1997, 27(7), 34.
S. Liu, Z. Luo, and A. D. Hamilton.
Rapid and highly selective cleavage of ribonucleoside 2',3'-cyclic monophosphates by dinuclear Cu(II) complexes.
Angewandte Chemie International Edition English 1997, 36(23), 2678-2680.
DOI: 10.1002/anie.199726781
M. W. Peczuh, A. D. Hamilton, J. Sanchez-Quesada, J. de Mendoza, T. Haack, and E. Giralt.
Recognition and stabillization of an α-helical peptide by a synthetic receptor.
Journal of the American Chemical Society 1997, 119(39), 9327-9328.
DOI: 10.1021/ja970951l
H. Chen, W. S. Weiner, and A. D. Hamilton.
Recognition of neutral species with synthetic receptors.
Current Opinion in Chemical Biology 1997, 1(4), 458-466.
DOI: 10.1016/S1367-5931(97)80039-7
Y. Qian, S. M. Sebti, and A. D. Hamilton.
Peptidomimetic inhibitors of farnesyltransferase: An approach to new antitumor agents.
In A. Abell, editor, Advances in Peptidomimetic Chemistry, volume 1, pages 165-192. Jai Press, 1997.
K. Miquel, A. Pradines, J. Sun, Y. Qian, A. D. Hamilton, S. M. Sebti, and G. Favre.
GGTI-298 induces G0/G1 block and apoptosis whereas FTI-277 causes G2/M enrichment in A549 cells.
Cancer Research 1997, 57(10), 1846-1850.
S. M. Sebti and A. D. Hamilton.
Anticancer activity of farnesyltransferase and geranylgeranyltransferase I inhibitors: Prospects for drug development.
Expert Opinion on Investigational Drugs 1997, 6(11), 1711-1714.