Zelda potentiates morphogen activity by increasing chromatin accessibility.
Curr Biol (2014 Jun 16) PMC4075064 free full-text archive
Foo SM, Sun Y, Lim B, Ziukaite R, O'Brien K, Nien CY, Kirov N, Shvartsman SY, Rushlow CA
Temporal coordination of gene networks by Zelda in the early Drosophila embryo.
PLoS Genet (2011 Oct) PMC3197689 free full-text archive
Nien CY, Liang HL, Butcher S, Sun Y, Fu S, Gocha T, Kirov N, Manak JR, Rushlow C
The zinc-finger protein Zelda is a key activator of the early zygotic genome in Drosophila.
Nature (2008 Nov 20) PMC2597674 free full-text archive
Liang HL, Nien CY, Liu HY, Metzstein MM, Kirov N, Rushlow C
Threshold response of C15 to the Dpp gradient in Drosophila is established by the cumulative effect of Smad and Zen activators and negative cues.
Development (2006 Dec) PMID: 17092951
Lin MC, Park J, Kirov N, Rushlow C
Peak levels of BMP in the Drosophila embryo control target genes by a feed-forward mechanism.
Development (2005 Apr) PMID: 15728670
Xu M, Kirov N, Rushlow C
Transcriptional regulation of the Drosophila gene zen by competing Smad and Brinker inputs.
Genes Dev (2001 Feb 01) PMC312624 free full-text archive
Rushlow C, Colosimo PF, Lin MC, Xu M, Kirov N
The Drosophila gene brinker reveals a novel mechanism of Dpp target gene regulation.
Cell (1999 Feb 19) PMID: 10052458
Jazwinska A, Kirov N, Wieschaus E, Roth S, Rushlow C
Isolation and characterization of a new gene encoding a member of the HIRA family of proteins from Drosophila melanogaster.
Gene (1998 Jun 08) PMID: 9611274
Kirov N, Shtilbans A, Rushlow C
puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila.
Genes Dev (1998 Feb 15) PMC316530 free full-text archive
Martin‑Blanco E, Gampel A, Ring J, Virdee K, Kirov N, Tolkovsky AM, Martinez‑Arias A
The transcriptional corepressor DSP1 inhibits activated transcription by disrupting TFIIA-TBP complex formation.
EMBO J (1996 Dec 16) PMC452533 free full-text archive
Kirov NC, Lieberman PM, Rushlow C
The Drosophila dorsal morphogen represses the tolloid gene by interacting with a silencer element.
Mol Cell Biol (1994 Jan) PMC358420 free full-text archive
Kirov N, Childs S, O'Connor M, Rushlow C
Conversion of a silencer into an enhancer: evidence for a co-repressor in dorsal-mediated repression in Drosophila.
EMBO J (1993 Aug) PMC413585 free full-text archive
Kirov N, Zhelnin L, Shah J, Rushlow C
In vitro transcription through nucleosomes by T7 RNA polymerase.
EMBO J (1992 May) PMC556653 free full-text archive
Kirov N, Tsaneva I, Einbinder E, Tsanev R
The complexity of 75S premessenger RNA in balbiani ring granules studied by a new RNA band retardation assay.
Nucleic Acids Res (1991 Jun 25) PMC328337 free full-text archive
Kirov N, Wurtz T, Daneholt B
Segregation of nucleosomes in replicated mouse alpha-globin gene.
Biochem Biophys Res Commun (1987 Jun 30) PMID: 3038089
Kirov N, Tsaneva I, Yaneva J, Tsanev R
Activated murine alpha-globin gene is not preferentially associated with the nuclear matrix.
Int J Biochem (1986) PMID: 3005069
Kirov N, Tsanev R
Presence of nucleosomal repeat in the transcribed alpha globin gene of induced murine erythroleukemia cells.
Biochem Biophys Res Commun (1985 Jul 16) PMID: 3861179
Kirov N, Tsaneva I, Tsanev R
Nuclear matrix and transcriptional activity of the mouse alpha-globin gene.
J Mol Biol (1984 Dec 15) PMID: 6597312
Kirov N, Djondjurov L, Tsanev R