Joseph Osmundson

Clinical Assistant Professor of Biology

Education

  • 2012 Ph.D., The Rockefeller University
  • 2006 M.S., Université Joseph Fourier – Fulbright Fellow
  • 2005 B.A., Carleton College

Areas of Research/Interest

My research uses a wide variety of tools, from structural biology to bioinformatics, to understand a cell’s essential molecular machines. Using yeast as a model system, my work as a postdoc showed how the cell’s replication and transcription machinery coordinate their simultaneous use of the DNA template. My ongoing research examines the cell’s response to replication stress, and I’m developing discovery-based teaching modules to incorporate this research into undergraduate teaching labs

FELLOWSHIPS/HONORS

  • 2015-2017 American Cancer Society Postdoctoral Fellowship
  • 2005-2006 Fulbright Fellowship

Publications

Date of these PubMed search results: March 24 2020
Get the current Pubmed search results

  1. Processing of eukaryotic Okazaki fragments by redundant nucleases can be uncoupled from ongoing DNA replication in vivo.
    Nucleic Acids Res (2019 Feb 28) PMC6393292 free full-text archive
    Kahli M, Osmundson JS, Yeung R, Smith DJ
  2. Pif1-family helicases cooperatively suppress widespread replication-fork arrest at tRNA genes.
    Nat Struct Mol Biol (2017 Feb) PMC5296403 free full-text archive
    Osmundson JS, Kumar J, Yeung R, Smith DJ
  3. Doing that thing that scientists do: A discovery-driven module on protein purification and characterization for the undergraduate biochemistry laboratory classroom.
    Biochem Mol Biol Educ (2015 May-Jun) PMID: 25735767
    Garrett TA, Osmundson J, Isaacson M, Herrera J
  4. RNA-Seq reveals differential gene expression in Staphylococcus aureus with single-nucleotide resolution.
    PLoS One (2013) PMC3792026 free full-text archive
    Osmundson J, Dewell S, Darst SA
  5. Structure and function of CarD, an essential mycobacterial transcription factor.
    Proc Natl Acad Sci U S A (2013 Jul 30) PMC3732983 free full-text archive
    Srivastava DB, Leon K, Osmundson J, Garner AL, Weiss LA, Westblade LF, Glickman MS, Landick R, Darst SA, Stallings CL, Campbell EA
  6. Biochemical insights into the function of phage G1 gp67 in Staphylococcus aureus.
    Bacteriophage (2013 Jan 1) PMC3694059 free full-text archive
    Osmundson J, Darst SA
  7. Phage-encoded inhibitor of Staphylococcus aureus transcription exerts context-dependent effects on promoter function in a modified Escherichia coli-based transcription system.
    J Bacteriol (2013 Aug) PMC3754564 free full-text archive
    Montero‑Diez C, Deighan P, Osmundson J, Darst SA, Hochschild A
  8. Promoter-specific transcription inhibition in Staphylococcus aureus by a phage protein.
    Cell (2012 Nov 21) PMC3604623 free full-text archive
    Osmundson J, Montero‑Diez C, Westblade LF, Hochschild A, Darst SA
  9. Activation of classical pathway of complement cascade by soluble oligomers of prion.
    Cell Microbiol (2007 Dec) PMID: 17991046
    Dumestre‑Perard C, Osmundson J, Lemaire‑Vieille C, Thielens N, Grives A, Favier B, Csopaki F, Jamin M, Gagnon J, Cesbron JY