Banani Chakraborty, Ramalingaswami Fellow on the Faculty of Chemical Engineering at the Indian Institute of Science (and NYU alumnus - Ph.D 2008 in the Seeman Group), will deliver a seminar entitled, "Merging top down & bottom up nanotechnology: customised nanopore and nanochip based biosensors." Hosted by Jim Canary.
To join on zoom, click here:
For more information about Banani Chakraborty, click here.
Abstract: DNA is a well-known biomolecule, which proved to have function in biology as well as in the material world. Since 1982 DNA has been used widely to build nanostructures in 1D, 2D and 3D with very high precision and programmability in nanometer to micron scale. Past decades have seen tremendous progress in complex structure formation with DNA origami in 2D and 3D. The power of bottom up nanotechnology is to form structures below 50nm with very high precision. Focus has been shifted in past few year from designing structures to making those functional for various applications. Having the flexibility to modify DNA chemically to perform desired functions on DNA origami as well as modifying DNA sequences specifically for host guest complexation (aptamer technology) is being studied to prepare the 1st DNA nano-biochip of its kind which will enable the detection of multiple targets in parallel in nanometer size chip and via customised nanopores made of DNA origami. Individual sensors are tested with minute details using single molecule fluorescence in bulk as well as on surface. The limit of detection number of target is bound by the visualization technique detection limit; such as AFM, SEM. We are also focusing on forming hybrid nano-materials to enhance the precision and robustness of nano-fabrication and targeted cargo delivery.
Note: In addition to the general seminar, there will be an Alumni Career Chat hosted by the Vanadium Chapter of Iota Sigma Pi at 4:00 p.m. in room 1018 Silver. All are welcome in-person only.