Liquid-liquid phase separation of cytoplasmic and nuclear components into biomolecular condensates is emerging as a fundamental mechanism of cellular organization. These condensates are spatially segregated, but open systems, which can serve as specialized regions for biochemical reactions, dynamically sequester components or act as organizational hubs for signaling networks.
Phase separation regulates processes as diverse as transcription, stress granule formation and actin polymerization. Moreover, an accumulating body of evidence suggests that dysregulation of these phase transitions may contribute to neurodegenerative diseases, including ALS and prion diseases, as well as to cancer.
This one day symposium will bring together scientists from academia and industry to dissect the latest advances in the field of biological phase separation and discuss the implications for human disease.
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Call for Abstracts
Abstract submissions are invited for a poster session. For complete submission instructions, please visit our online portal. The deadline for abstract submission is Friday, December 21, 2018.