Biological Imaging Core

The Department's Core Imaging Facility has several different types of microscopes that are housed in the Center for Genomics and System Biology and in the Brown Building. These include a Leica SP5, Leica SP8, and a Zeiss 880 Airyscan point-scanning laser confocal microscopes. The Zeiss is configured with a multiphoton laser, while the Airyscan set up allows for highly sensitive, high resolution imaging in live and fixed tissues. In addition to these confocal systems, there are several types of upright and inverted microscopes each configured with different types of optical and illumination systems. Image analysis is provided through dedicated computer workstations running the Leica LAS and the Zeiss Zen analysis software as well as Imaris. The mixture of microscope systems located in the Imaging Facility provide microscope users a variety of ways to visualize and analyze their microscopic images.

In addition, a fluorescent capable Leica AS Laser Capture Dissection Microscope (LCM) allows cutting cells or sub-cellular structures as small as 5 microns. This system has been used to isolate cells for downstream RNA analysis. The LCM has also been used for laser microdissections on tissues as thick as 100 to 150 microns.

FOR EQUIPMENT USE, PLEASE ACCESS OUR NEW LABGEAR RESERVATION SYSTEM

Questions regarding these microscopes and reservations should be directed to Dr. Ignatius P. Tan (ignatius.tan@nyu.edu).