News Archive

Gresham lab develops method to visualize a genetic mutation
Gresham lab develops a method that yields, for the first time, visualization of a gene amplifications and deletions known as copy number variants in single cells.

Small lab and Thorton lab (University of Chicago) create flies with ancient genes to study the evolution of embryonic development
The fruit flies created carry reconstructed ancient genes to reveal how ancient mutations drove major evolutionary changes in embryonic development.

Rockman lab find new genetic interdependence between mothers and their offspring
The distinctive genetic processes of early development help explain patterns of animal development in nature and across the evolutionary tree.s.

Neville Sanjana wins DARPA 2018 Young Faculty Award for Precise Gene Repair
Neville Sanjana has received the Defense Advanced Research Projects Agency’s Young Faculty Award for his proposal to develop new tools for precise gene repair using CRISPR.

Small lab finds mechanisms that control where transcription factors bind
The results help illuminate how cells acquire distinct functions as the embryo matures.

Coruzzi lab identifies the temporal logic of regulatory genes affecting nitrogen use efficiency in plants
Gloria Coruzzi and her team adopted a time-based machine-learning approach to deduce the temporal logic of nitrogen signaling in plants from genome-wide expression data.

Claude Desplan elected to the National Academy of Sciences
Desplan focuses on the generation of neural diversity and the establishment and evolution of retinal and brain circuitry that underlies color and motion vision.

Satija lab develops new algorithm enabling data integration at single-cell resolution
The new method has implications for better understanding how different groups of cells change during disease progression, in response to drug treatment, or across evolution.

Desplan lab sheds light on the perception of motion
The discovery, which appears in the journal Cell, offers new pathways for understanding the fundamental processes by which circuits in the brain form to process visual information.

Annual Darwin Lecture hosts David Kingsley, discussing evolutionary patterns we share with creatures of the sea
Biology Department will host David Kingsley, an evolutionary biologist at Stanford University, for “Fishing for the Secrets of Vertebrate Evolution,” at its annual Darwin Lecture, on Friday, Feb. 23, 4 p.m.

Rich Bonneau appointed Director of NYU’s Center for Data Science
Rich Bonneau, Professor of Biology and Computer Science, is the new director of the NYU Center for Data Science. Read more...
Biology Department Outreach at 2017 World Science Festival
Alison Mello from the Biology Teaching Labs worked with NYU-MRSEC, NYU-STEP and BioBus to showcase the work of talented STEP high school students and CSTEP undergraduates at the 2017 World Science Festival.
Vogel, Schneider-Paolantonio Promoted
Christine Vogel and Katie Schneider-Paolantonio have both been recently promoted.
Incoming PhD Class of 2017
We welcome 13 PhD Class of 2017 students.
The Ercan lab publishes in eLife
Cooperation between a hierarchical set of recruitment sites targets the X chromosome for dosage compensation
Biologist Explains One Concept in 5 Levels of Difficulty – CRISPR
WIRED challenged biologist Neville Sanjana to explain CRISPR to 5 different people; a child, a teen, a college student, a grad student, and a CRISPR expert.
Tyler Volk publishes new book
Quarks To Culture: How We Came To Be
Ercan, Hochwagen Promoted
Sevinc Ercan and Andreas Hochwagen have both been recently promoted.
Mike Rampino publishes new book
Cataclysms: A New Geology for the Twenty-First Century
Former Birnbaum lab postdoc Idan Efroni named HHMI International Research Scholar
Idan Efroni, a former postdoc in Ken Birnbaum's lab, was chosen as an international research scholar, exceptional early-career scientists poised to advance biomedical research aross the globe.
Mike Rampino and team discover evidence for large impact crater
In the journal Terra Nova, Mike Rampino and co-workers describe a potential 250km diameter impact crater buried under the sea floor near the Falkland Islands. This would be one of the largest known impact structures on Earth.
Neville Sanjana receives 2017 MRA young investigators award and 2017 Kimmel Scholar award
Neville Sanjana has received a 2017 Melanoma Research Alliance Young Investigator Award and a 2017 Kimmel Scholar Award to fund the lab’s work in leveraging the gene-editing tool CRISPR to comprehensively survey mutations that allow cancer cells to resist immunotherapy treatment.
Steve Small, Katie Schneider-Paolantonio and Alex Grote receive 2016-2017 teaching awards
Congratulations to Steve Small and Katie Schneider-Paolantonio for both winning the Golden Dozen Teaching Award, an award to faculty for outstanding teaching.
Congratulations Alex Grote, a PhD student in Elodie's lab, for winning the Outstanding Teaching Award for graduate and adjunct teachers.
NYU Students Tour DDC’s Washington Square Infrastructure Project
Katie Schneider-Paolantonio and her New York Underground undergraduate class toured an NYC Department of Design and Construction project. The field trip linked all the utilities that the students learned about in class and allowed them to peer into the complex underground network below their feet.
The Satija lab publishes in Science
Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors.
19th annual M.S. poster session winners
First Place :Xiang Niu, Satija & Christiaen Labs and Anastasios Mirisis, Carew Lab
Second Place: Patrice Delaney, Kirov & Rushlow Labs
Third Place: Yixuan Ma, Ghedin Labs and Pedro M. Herrero Vidal, Klann Lab
The Broyde lab publishes in Biochemistry
Nucleosome histone tail conformation and dynamics: Impacts of lysine acetylation and a nearby minor groove benzo[a]pyrene-derived lesion.
Christine Vogel Receives 2017 US HUPO Award
Christine Vogel was selected as a winner of the 2017 Robert J. Cotter New Investigator Award given by US HUPO.
The Desplan lab explains the generation of neural diversity in Nature
Integration of temporal and spatial patterning generates neural diversity.
Rewiring Chordate Myogenesis
Tolkin and Christiaen publish insights into the rewiring of chordate myogenesis programs in Development
Li Lab Publishes in Molecular Cell
Centromere is essential for chromosome segregation, but how centromere is properly established and maintained is still poorly understood.
2016 DG Symposium
Evolutionary Developmental Biology
Join co-organizers Lionel Christiaen, Esteban Mazzoni and Matt Rockman, Biology chair Justin Blau and our outstanding line-up of speakers.
Broyde received the Division of Toxicology 2016 Founders’ Award
Suse Broyde and Nicholas Geacintov received the American Chemical Society Division of Toxicology’s 2016 Founders’ Award
Siegal Awarded NIH MIRA Grant
Mark Siegal Awarded New NIH Maximizing Investigators' Research Award
Carlton lab malaria research featured in Nature Genetics
Hupalo, Luo, and Carlton's latest malaria research featured in Nature Genetics
Ercan lab publishes in Genetics
Max Kramer of the Ercan lab published in Genetics on X chromosome copy number
Purugganan lab's Meyer featured on cover of Nature Genetics
Meyer, Purugganan's latest research featured on cover of this month's Nature Genetics
Katari and Jain: TCF7L1 Modulates Colorectal Cancer Growth
Katari and Jain publish in Scientific Reports: TCF7L1 Modulates Colorectal Cancer Growth
In memoriam Dr. Roger Yonchien Tsien
Roger Tsien 2008 Nobel Laureate for the discovery and development of the green fluorescent protein recently and unexpectedly passed away. New York University Biology researchers wish to memorialize Tsien’s contribution’s with a collage of our favorite GFP images from our own work.
Biology Honors Student Class 2016
Pursuing a scientific career is intellectually exciting and practically important to society. Succeeding in a scientific career is both an art and a science. Being successful requires intelligence and expertise in the laboratory, but equally important, it requires skills in scientific writing, oral communication, and ethics. Undergraduate Biology Honors students who are conducting independent laboratory-based research projects perform project-based learning through reading scientific papers, and through writing and oral communication of scientific results, while also gaining exposure to issues in scientific ethics and career paths.
Jane Carlton's presentation at World Malaria Day Symposium
Jane Carlton discusses the current work of the Center for the Study of Complex Malaria in India at the 2016 World Malaria Day Symposium & Johns Hopkins Bloomberg School of Public Health Centennial Celebration.
Eichenberger Publishes 'The Bacterial Spore'
Eichenberger Co-Edits New Book 'The Bacterial Spore,' Published by ASM Press
Killing the Messenger
Killing the Messenger: Post-transcription regulation of mRNA responds to dynamic environments
Killing the Messenger
Killing the Messenger: Post-transcription regulation of mRNA responds to dynamic environments
2016 CGSB Symposium
Dosage Matters: Control and Consequences of Gene Copy Number
Join Co-Organizers David Gresham and Sevinc Ercan, CSGB Director Jane Carlton, Dean Michael Purugganan and our outstanding lineup of speakers, as well as an NYU post-doc poster session. Lunch will be provided.
Johns Hopkins World Malaria Day Symposium
Johns Hopkins World Malaria Day Symposium Program Announced
Gunsalus lab publishes on structural protein modeling
Gan and Gunsalus published a paper in Nucleic Acids Research on structural modeling, showing that the ability of microRNAs to recognize diverse mRNA targets requires conformational adaptation of the Argonaute protein.
Kussell lab publishes in Current Biology
Restriction-modification (RM) systems protect nearly all prokaryotes from parasitic DNA. Pleska et al. show that a subpopulation of bacteria carrying an RM system suffers from autoimmunity--a stochatstic process, which temporarily disrupts the host's genome integrity.
Ghedin lab publish flu strain diversity in Nature Genetics
Ghedin and colleagues’ research, which examined samples from the 2009 flu pandemic in Hong Kong, shows that minor strains are transmitted along with the major flu strains and can replicate and elude immunizations.
Rockman Lab receives award for Diatom Research
CGSB faculty member Matt Rockman has been awarded funds from an $8 Million Moore Foundation Marine Microbiology Initiative.
Vogel lab deciphers dynamics of protein expression
The Vogel Lab at CGSB has deciphered the dynamics of mammalian mRNA and protein expression during protein misfolding stress.
Purugganan lab reveals new aspects of dynamic gene expression
Most previous studies into the effect of the environment on plant gene expression have been carried out under controlled conditions in a laboratory; this study analyzed rice plants grown in the Phillippines in rainfed and irrigated fields during two distinct tropical seasons. Its analysis shows that temperature and light levels have a strong impact on gene expression.
Bonneau, Eichenberger and collaborators publish new model
Arrieta Ortiz et al describe a new computational framework, which generates an expanded and more accurate transcriptional regulatory network for Bacillus subtilis.
Video from 8th Annual Developmental Genetics Symposium
Presentations from the 2015 8th Annual Developmental Genetics Symposium.
Max Kramer publishes on X chromosome expression in C. elegans
Max Kramer from the Ercan lab published the temporal dynamics of molecular mechanisms that regulate X chromosome expression in C. elegans
Stolfi and Christiaen published a paper in Nature
Migratory neuronal progenitors arise from the neural plate borders in tunicates.

2015 Developmental Genetics Symposium
Join Keynote speakers Elaine Fuchs (Rockefeller University) and Michael Levine (Princeton University) plus 8 noted scientists
CGSB researchers interview subsistence farmers in Africa
NYU researchers team up with researchers from AfricaRice to interview subsistence farmers still growing a native rice that is rarely sold and is rapidly being replaced by Asian rice. Their goal was to understand how...
Purugganan awarded Silver Professorship for 2015-16
Michael Purugganan has been awarded one of the prestigious Silver Professorships for the 2015-2016 Academic year. Dr. Purugganan was recognized for this endowed professorship based not only on his contributions to the field of evolutionary biology, but also because of his outstanding focus on pedagogy and mentorship at both the graduate and undergraduate levels. A formal induction ceremony and reception will be held on March 29th, 2016. Congratulations!
Alex Mogilner published a paper in Nat Cell Biol
Search-and-capture model of mitotic spindle assembly suggests that large kinetochores accelerate the spindle assembly but increase number of errors, so how can the spindle assemble both fast and accurately is unclear. Joint work of Mogilner and Khodjakov labs shows that kinetochores' shape and size change in prometaphase, which, together with delicate geometry of lateral microtubule-kinetochore captures, both accelerates the assembly and improves its accuracy.
Blau Lab publishes paper in Cell on neuronal plasticity
PhD student, Afroditi Petsakou discovered that daily rhythms in the plasticity of circadian pacemaker neurons are regulated by rhythmic transcription of Pura, a Rho1 GEF.
Hochwagen Lab Reveals Design Principles of Meiotic Chromosomes
Research by Xiaoji Sun and Tovah Markowitz in the Hochwagen lab has uncovered a key mechanism that allows condensed meiotic chromosomes to be transcribed. The results, published recently in eLIFE, show that chromatin is flexibly anchored to the chromosome axis by cohesin rings. This way the axis simply moves out of the way of transcription without losing condensation.
Gustavo Silva receives an NIH K99 award
The post-doctoral fellow Gustavo M. Silva received a NIH K99/R00 “Pathway to Independence Award” to study the roles of protein ubiquitination in response to environmental stress.
Zakas and Rockman published a paper in Evolution and Development
Genomic insights into the evolution of animal development
Video from 14th Annual Symposium of the NYU CGSB
Keynote presentation "CRISPR Biology - From Basic Science to Breakthrough Technology" by Dr. Jennifer Doudna (University of California, Berkeley) from the 2015 14th Annual Symposium of the New York University Center for Genomics and Systems Biology.
2015 Genome Symposium
The 2015 NYU CGSB Symposium, "From Genomes to Systems: Celebrating 20 years of Genomics" will take place on Friday, May 22, 2015.
Christiaen Lab published a review in Nature
Christiaen Lab published a review in Nature on development and evolution of the heart and head muscles.
Satija publishes algorithm for spatially mapping single cell RNA
In Nature Biotechnology, Satija et al. describe the Seurat algorithm to infer the spatial localization of single cells during Zebrafish embryogenesis based on RNA-seq data.
Duncan Smith has been named a 2015 Searle Scholar
The Searle Scholars Program supports research of outstanding individuals who have recently begun their appointment at the assistant professor level. Each year 15 new individuals are named Searle Scholars and awarded flexible grants of $300,000 over three years.
Christiaen Lab published a new review in Current Opinion
Kaplan, Razy-Krajka and Christiaen published a new review on heart and head muscles development and evolution in Current Opinion in Genes and Development, titled “Regulation and evolution of cardiopharyngeal cell identity and behavior: insights from simple chordates”.
Eichenberger lab publishes a paper in PLoS Genetics
In collaboration with scientists at Lisbon University and Emory, the Eichenberger lab reports the functional characterization of an anti-sigma factor regulating canalization of gene expression during sporulation in Bacillus subtilis,
Alex Mogilner published a paper in Mol Biol Cell
Classical models of leading-edge protrusion rely on a Arp2/3-dependent treadmilling of dendritic actin network. However, in the absence of the Arp2/3 complex fibroblast cells maintain an ability to move. Joint work of Mogilner and Rong Li labs shows that cells extend formin-driven filopodia and build actin-myosin arcs in between filopodia, so that contraction of these arcs acting against membrane tension advances the cell leading edge.
Does Dark Matter Cause Mass Extinctions and Geologic Upheavals?
Michael Rampino concludes that Earth’s infrequent but predictable path around and through our Galaxy’s disc may have a direct and significant effect on geological and biological phenomena occurring on Earth.
Two transcription factors that promote Lateral Root Formation
An “education kit” was designed and constructed for disseminating to teaching institutes worldwide a collection of transgenic reporter Arabidopsis plants that allows students to explore the molecular genetics of root development.
Olivia Wilkins was quoted in The Atlantic Magazine
The Atlantic Magazine recently published an article about NYU’s Science Communication Workshops taught by Steve Hall. Olivia Wilkins, a post-doctoral fellow who studies plant genetics at NYU's CGSB recently took Hall's workshop and was interviewed for the story.
Swift Publishes Career Essay in Science
Joseph Swift, a PhD student in the Coruzzi lab, recently published an essay in the Careers Section of Science.
Carlton Project Covered in New York Times
Jane Carlton’s Grand Challenge project was recently covered by the New York Times Science section in an article, “What Our Sewage Can Teach Us”.
Grand Challenge: Mapping NYC's MetaGenome
In this video, members of one winning team—Biology Professor Jane Carlton, director of the NYU Center for Genomics and Systems Biology, and Ari Patrinos, deputy director for research at the Center for Urban Science and Progress...
Synchronize your watches
The Blau Lab published a paper in the September issue of PLOS Biology in which they described how clocks in individual neurons synchronize with each other for a coherent internal timer.
Adaptive evolution in chemostats
David Gresham and PhD student, Jungeui Hong, have published a review of the functional basis of adaptive evolution of yeast and bacteria in chemostats.
Yeast gene regulatory network
David Gresham has published a gold standard yeast gene regulatory network in a study led by Alexander Statnikov at the NYU School of Medicine.
Defining the guidelines for the nomenclature of genetic elements
Alberto Stolfi and Lionel Christiaen contribute to defining the guidelines for the nomenclature of genetic elements in tunicates
Alberto Stolfi published a paper in eLIFE
Alberto Stolfi from the Christiaen lab published a paper in eLife, in collaboration with Elijah Lowe, Billie J Swalla and C Titus Brown. This shows that divergent mechanisms control conserved gene expression and developmental patterns between distant ascidian species.
Christiaen lab profiles pigment cell precursors
In collaboration with colleagues at the Stazione Zoological Anton Dohrn in Naples, Italy, a paper was published in Nature Communications, where they dissected the transcriptional dynamics underlying pigment cell specification.
Temporal Patterning of Death and Survival
Claire Bertet and colleagues in the Desplan lab describe in a recent issue of Cell how temporal patterning of neuronal stem cells controls the death of neurons in the Drosophila optic lobes.
Vogel Lab Awarded NIH Grant
CGSB Assistant Professor Christine Vogel was recently awarded a 4-year NIH grant to model protein expression changes.
Rates of protein synthesis and degradation
Konstantine Tchourine from the Vogel and Bonneau labs has published a computational study in Molecular BioSystems with a team of co-workers.
Maritz Publishes Front Cover Review Article
PhD Student Julia Maritz from the Carlton lab published a review as a front cover article in the July issue of Trends in Parasitology.
Desplan lab defines the circuit for motion detection
Rudy Behnia and Claude Desplan describe in an upcoming issue of Nature how a set of four neurons in the optic lobes of Drosophila implement motion detection of light and dark edges.
Coruzzi Lab Discovers New Hit-and-Run Model of Transcription
The Coruzzi lab has identified a new “hit-and-run” transcription mechanism. The findings were published in a recent issue of PNAS.
Video from 13th Annual Symposium of the NYU CGSB
Presentations from the 2014 13th Annual Symposium of the New York University Center for Genomics and Systems Biology.
Nematode X Chromosomes
In a recent Genetics paper, Sarah Albritton (Ercan lab) shows that the nematode X chromosomes have higher female-biased and lower male-biased expression.
Elodie Ghedin Featured in Women in Science Video Series
CGSB faculty member Elodie Ghedin was recently highlighted in a video series celebrating women in science.
Carlton's Dirty Money Project Covered by WSJ
The Wall Street Journal recently published an article covering the findings of the Carlton lab's Dirty Money Project.
2014 Genome Symposium
The 2014 NYU CGSB Symposium, "Genomes Evolving" took place on Friday, June 6, 2014.
Rosenberg defines the evolution of insect segmentation
Using an unusual experimental model, Miriam Rosenberg proposed that the wasp Nasonia exhibits a dual mode of segmentation: long germ like Drosophila at the anterior of the embryo, and short germ, with a segmentation clock at its posterior, as in most basal insects. This allowed her to suggest an evolutionary path for early embryonic development.
Desplan lab publishes article on Science
Robert Johnston and Claude Desplan described in a recent issue of Science how each of the two alleles of the gene spineless, which control the stochastic expression of Rhodopsin photopigments in the Drosophila retina, are turned ON or OFF randomly in photoreceptor cells. When the two alleles make different decisions, communication between them allows the cell to coordinate expression.
Li Lab Awarded NSF Grant
Fei Li, an assistant professor in the Department of Biology, has been awarded a three-year NSF grant to study epigenetic inheritance, a process which, when disrupted, results in genomic instability and developmental disorders in both plants and humans.
Wernet publishes mechanism of polarized light detection in flies
Mathias Wernet deciphered the transcriptional network that specifies the region of the Drosophila eye responsible for the detection of the vector of light polarization that allows insects to navigate when the sun is not present.
Malaria Host-Pathogen Interaction Center interviews Jane Carlton
Dr. Jane Carlton discusses her early interest and current research of Malaria at the Emory University Malaria Host-Pathogen Interaction Center.
NYU's 2014 Darwin Lecture
"From Darwin to DNA: Digging for Genes that Affect Behavior" This event is free and open to the public.
Optimized method for next-generation genetic screens
David Gresham recently published an optimized method for next-generation genetic screens in the open access journal of the Genetics Society of America, G3.
Hong and Gresham publish study in PLoS Genetics
PhD student, Jungeui Hong and David Gresham have published a high resolution study of adaptive evolution of budding yeast in nutrient-limited environments.
Purugganan named to HFSP’s Council of Scientists
CGSB faculty member Michael Purugganan was recently welcomed as the new U.S. representative to the Human Frontier Science Program’s Council of Scientists.
CGSB Post-Doc Co-Founds Botanical Blends Company
CGSB post-doctoral fellow, Rachel Meyer, recently co-founded a botanical blends company called “Shoots and Roots Bitters”.
Crop Domestication Genetics and Genomics
In the December 2013 volume of Nature Reviews Genetics, CGSB post-doctoral fellow ,Rachel Meyer, and Michael Purugganan co-wrote a review article on the state of the field of crop domestication genetics and genomics.
Lionel Christiaen receives 2014 Young Investigator Awards
Lionel Christiaen was awarded with Young Investigator Award.
Protein Expression Under Pressure
In a Perspective article in Science, Christine Vogel discusses recent findings on a recurring theme in expression regulation.
Vogel Lab Receives NSF EAGER Grant
The Vogel lab, in collaboration with Dennis Shasha from the NYU Courant Institute of Mathematical Sciences, received funding for their research on predicting protein degradation.
2013 DG Symposium
6th Annual NYU Developmental Genetics Symposium "From Stem Cells to Organs" on December 6, 2013
CGSB Faculty Positions Available
The NYU Center for Genomics and Systems Biology is now hiring.
CGSB Researchers Among Winners of Grand Challenge Competition
Congratulations to several CGSB researchers who are a part of one of two research teams being awarded $250,000 by NYU for the “Grand Challenge” competition.
Gresham Lab Awarded 5-Year NIH Grant
The Gresham lab has been awarded a 5 year grant by the NIGMS to study the regulation of cell growth and quiescence in eukaryotic cells.
Coruzzi Lab Featured
An article and slideshow featuring the work of Gloria Coruzzi and her lab is currently being featured on the NYU Stories website.
Siegal Earns 4-year NSF Grant
The National Science Foundation has awarded Mark Siegal a four-year grant to study cryptic genetic variation in the fly Drosophila melanogaster, a well established model organism for genetics research.
Siegal Lab Questions Long-held View of Robustness
In work published in PLoS Genetics, Dr. Joshua Richardson and Siegal lab colleagues refute a gene's role in suppressing the effects of mutations.
Ziv Validates Decades-old Monod Prediction
Ph.D. candidate Naomi Ziv, working with Drs. David Gresham and Mark Siegal in the CGSB, has validated a longstanding prediction about nutrient-limited growth in microbes.
Bonneau Named As A Top 10 Life Science Leader
CGSB Scientist, Richard Bonneau, was recently named as one of the top 10 life science leaders under age 40 by Genetic Engineering & Biotechnology News.
Fei Li Named a Pew Scholar
Assistant Professor Fei Li was recently selected as a Pew Scholar in the Biomedical Sciences by The Pew Charitable Trusts.
Olivia Wilkins
Olivia Wilkins, a post-doctoral fellow in the CGSB, was recently named as one of 13 winners of the NSF/Gates Foundation BREAD Challenge Prize.
Temporal patterning of Drosophila
Xin Li and Ted Erclik from Desplan Lab published a full article in Nature, analyzing the medulla processes visual information coming from inner photoreceptors R7 and R8 and from lamina neurons in the Drosophila optic lobes. It describes how precise temporal patterning of neural progenitors generates these different neural types.
2013 Genome Symposium
Thank you to everyone who participated in the 12th Annual Genomics Symposium entitled "Synthetic Biology & Microbial Ecology". The symposium took place on June 7th.
Genome of Dates
CGSB Professor and NYU Dean for Science, Michael Purugganan, recently initiated the "100 Dates" project which will sequence the genomes of 100 date varieties.
Earth's Interior Cycles
NYU Biology's Michael Rampino and collaborator, Andreas Prokoph, recently published an analysis on the cyclical activity below the earth's surface.
Computational Method for Analyzing microRNA-mRNA Interactions
CGSB researchers have developed a computational method for analyzing the interactions of miRNAs with their mRNA targets in atomic detail.
Carlton Edits Books on Malaria Parasites
CGSB Professor Jane Carlton has edited a new book entitled "Malaria Parasites: Comparative Genomics, Evolution and Molecular Biology."
Broyde Lab Research Highlighted
The lab of Dr. Suse Broyde, in collaboration with the Geacintov lab in the NYU Chemistry Department, has obtained new insight on certain PAH-derived lesions.
Coruzzi Lab Member Attends Nobel Ceremony
Angela Fan (former member of the Coruzzi lab) was recently selected to attend the Nobel Ceremony for her work on natural variation of nitrogen sensing in Arabidopsis.
Carlton Named AAAS Fellow
CGSB Professor, Dr. Jane Carlton, along with three other NYU professors, was recently named a Fellow by the American Association for the Advancement of Science (AAAS).
Video tour of the new Irene Rose Sohn Zegar Memorial Greenhouse
NYU President John Sexton officially dedicated the new Irene Rose Sohn Zegar Memorial Greenhouse at the NYU Center for Genomics and Systems Biology on Wed. October 17th, 2012.
CGSB Faculty Position
The NYU Center for Genomics and Systems Biology is now hiring.
Inflammatory Cells
NYU researchers determine how imflammatory cells differ from stem cells, and affect the outcome of various diseases.
Blau in NYU Research Digest
Researchers at NYU and Einstein discover new ways neurons work together to ease the transition between sleep and wake.
Human and Monkey Malaria
Carlton lab publishes two papers, as the front cover of Nature Genetics, describing comparative analysis of several monkey malaria clade genomes.
Bish
Rebecca Bish, a post-doctoral fellow in the CGSB, was recently selected as one of three winners of the global competition for a Target Validation Grant from Sigma-Aldrich/SwitchGear Genomics.
David Gresham named Dupont Young Professor
Dr. David Gresham, an Assistant Professor in the NYU Biology Department’s CGSB has been named a Dupont Young Professor.
Ashley Bate
Ashley Bate, a Ph.D. student in the Eichenberger laboratory, has received a Communications Prize for best young speaker at the 5th European Spores Conference.
Bet-hedging in Yeast
CGSB faculty member finds mechanisms by which yeast hedge bets to enable some cells to survive in harsh unpredictable environments.
2012 Outstanding Teaching Awards
Two Biology Department Teaching Adjuncts receive 2012 Outstanding Teaching Awards from CAS. Congratulations!
Plant Expression in the Wild
In a paper published in and April 2012 issue of the journal PLoS Genetics, a CGSB research group led by Michael Purugganan explores how plant genes are turned on and off out in nature. The study helps in understanding how plant genomes can respond to natural environmental signals, and how they adapt to different habitats, agricultural fields and even to climate change.
Intel Third Place
Mimi Yen, a Stuyvesant High School student working with Prof. Matt Rockman at the NYU Center for Genomics and Systems Biology, won third place at the Intel Science Talent Search last March 12.
Ercan March of Dimes
Dr. Sevinc Ercan (left), assistant professor in the Department of Biology and Center for Genomics and Systems Biology, was awarded a prestigious 2012 Basil O’Connor Starter Scholar Research Awards by the March of Dimes Foundation. The award supports young and innovative scientists just embarking on their independent research careers, and provides funding to young investigators to start their own research projects on topics related to the March of Dimes mission.
NYU Abu Dhabi Conference
The NYU Abu Dhabi Conference on Genomics and Systems Biology II will be held at the Intercontinental Hotel in Abu Dhabi, United Arab Emirates on 14-16 February 2012.
Two NYC-Area High School Students Named INTEL Science Fair Finalists
Two high school students working on science-fair research projects with scientists at NYU’s Center for Genomics and Systems Biology (CGSB) are among the 40 national finalists for the international INTEL Science Talent Search competition for 2012.
CGSB’s Eichenberger
A ubiquitous family of bacteria, including the causative agent of anthrax and the most common cause of hospital-acquired infections in the United States, form spores that are extremely resistant to disinfection.
Tree of Life
Scientists at New York University’s Center for Genomics and Systems Biology, the American Museum of Natural History, Cold Spring Harbor Laboratory, and the New York Botanical Garden have created the largest genome-based tree of life for seed plants to date. Their findings, published today in the journal PLoS Genetics, plot the evolutionary relationships of 150 different species of plants based on advanced genome-wide analysis of gene structure and function. This new approach, called “functional phylogenomics,” allows scientists to reconstruct the pattern of events that led to the vast number of plant species and could help identify genes used to improve seed quality for agriculture.
Biologists Find New Function
A team of New York University biologists has uncovered a previously unknown role for a set cells within the female reproductive tract of insects. Their discovery, which appears in the journal PloS Biology, could lead into a range of innovations pertaining to insect life, from curbing the growth of mosquitos to bolstering the population of honey bees.
CGSB Scientist R. Bonneau and IBM Mark Computational Milestone
IBM announced a major computational milestone – surpassing 500,000 CPU years of computer time used by CGSB scientist Richard Bonneau and his Proteome Folding Project.
CGSB-led team awarded $2.3 M
Mutations are the raw material for evolution and a cause of many human diseases. With a recently awarded 4-year $2.3 M grant from the National Institutes of Health, Mark Siegal of the NYU CGSB will lead a collaborative effort with scientists at NYU, Stanford and the University of Georgia to characterize, with unprecedented precision, the rates and effects of different classes of mutations.

Cutting Edge Science
The CGSB was featured in a recent issue of the Washington Square News.
McDonnell Foundation Grant
Dr. Edo Kussell, assistant professor at the Center for Genomics and Systems Biology, was awarded a prestigious research award from the McDonnell Foundation as part of its 21st Century Science Initiative.
Recruitment
The NYU Center for Genomics and Systems Biology is now hiring.
Age-Old Questions
Scientists have devised a method to measure the impact of age on the growth rates of cellular populations, a development that offers new ways to understand and model the growth of bacteria, and could provide new insights into how genetic factors affect their life cycle. The research, which appears in Evolution: International Journal of Organic Evolution, was conducted by scientists at New York University and the University of Tokyo.
NSF Grant
Drs. Michael Purugganan and Rich Bonneau were awarded a 4-year $3.65 M grant by the NSF Plant Genome Research Program to figure out the genetic networks that allow rice to respond to temperature and water availability.
Senate Appropriations
The United States Senate Appropriations Committee conducted a site visit to CGSB professor Jane Carlton's seven year NIH project in India, from August 8-12, 2011.
NYU Genome Center Welcomes Dr. Jane Carlton
The NYU Center for Genomics and Systems Biology welcomes Dr. Jane Carlton as the newest addition to the faculty.
New NYU Genomics and System Biology Center Building Inaugurated
The new building for the NYU Center for Genomics and Systems Biology (CGSB) was officially inaugurated on June 1, 2011. The new building for the NYU Center is a revolutionary, 62,000-square foot “hub of science” located at the heart of the Washington Square campus. Keeping its original Greenwich Village façade this advanced science building houses open and interconnected state-of-the-art “loft laboratories” for teams of more than 200 researchers, including professors, postdoctoral scientists, and students.
Rice's origins point to China, NYU genome researchers conclude
Rice originated in China, a team of genome researchers has concluded in a study tracing back thousands of years of evolutionary history through large-scale gene re-sequencing. Their findings, which appear in the latest issue of the Proceedings of the National Academy of Sciences (PNAS), indicate that domesticated rice may have first appeared as far back as approximately 9,000 years ago in the Yangtze Valley of China. Previous research suggested domesticated rice may have two points of origin—India as well as China.
Kris Gunsalus talks about her latest Cell paper on gene networks
High-content screening for gene profiling has generally been limited to single cells. Here, we explore an alternative approach—profiling gene function by analyzing effects of gene knockdowns on the architecture of a complex tissue in a multicellular organism.
Two CGSB assistant professors make it on Cell's cluster of land
Cell recently cited 2 CGSB scientists (Richard Bonneau and Edo Kussell) for their landmark papers in Systems Biology. The scientists were highlighted in "Network News: Innovations in 21st Century Systems Biology" (Cell March 18, 2011, vol 144, p. 844).
Christine Vogel's work cited among top papers in Nature Biotech
CGSB assistant professor, Christine Vogel, was recently highlighted in Nature Biotechnology's 15th anniversary issue for her 2010 article, entitled: "Sequence signatures and mRNA concentration can explain two-thirds of protein abundance variation in a human cell line." Nature Biotechnology highlighted Vogel's article as one of its most cited articles in the last 5 years.
Endless Possibilities: The Campaign for The CGSB
Faculty from the Center for Genomics and Systems Biology describe the new home of the center at New York University and the research possibilities.
NSF Awards $3.75M to New York Plant Genome Consortium
The National Science Foundation has awarded a $3.75 million grant to a team of New York research and educational institutions to further develop BigPlant v1.0. This new computational tool enables the analysis of all currently sequenced plant genomes within a phylogenetic framework--that is, according to their evolutionary history. The aim is to further develop and mine the BigPlant v1.0 data matrix to discover the genes that evolved to give rise to important economic traits, such as the development of seeds.
Biologists Find Genetic Explanation for Evolutionary Change
A gene’s location on a chromosome plays a significant role in shaping how an organism’s traits vary and evolve, according to findings by genome biologists at New York University’s Center for Genomic and Systems Biology and Princeton University’s Lewis-Sigler Institute for Integrative Genomics. Their research, which appears in the latest issue of the journal Science, suggests that evolution is less a function of what a physical trait is and more a result of where the genes that affect that trait reside in the genome.