Robert Johnston and Claude Desplan described in a recent issue of Science how each of the two alleles of the gene spineless, which control the stochastic expression of Rhodopsin photopigments in the Drosophila retina, are turned ON or OFF randomly in photoreceptor cells. When the two alleles make different decisions, communication between them allows the cell to coordinate expression.
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The Desplan lab describes how communication between alleles coordinates stochastic choices
