Thursday, December 20th, 2012
The lab of Dr. Suse Broyde, in collaboration with the Geacintov lab in the NYU Chemistry Department, has obtained new insight on the ability of certain PAH-derived lesions to evade the DNA repair machinery. The work was recently highlighted in Science Daily. The findings, which were also published earlier this year in the February 2012 issue of Biochemistry, revealed that some lesions stabilize the DNA they damage, making it difficult for a certain repair protein to mark the lesion for repair. For more information, visit www.sciencedaily.com.