Molecular and Genetic Toxicology

PREREQUISITE: CELL BIOLOGY, BIOCHEMISTRY, OR PERMISSION OF THE INSTRUCTOR. SAME AS G48.2040.

Analyzes the modes by which organisms handle damage to DNA by physical and chemical agents, the mechanisms of converting damage to mutations, and the theoretical basis for carcinogenesis screening methods utilizing mutagenesis. Topics include systems for mutagenesis testing, mutational spectra, and inducible responses to DNA damage.