Chemical Biology Seminar Series: Jeff Schneider and Damian Ekiert
NYU Silver Center, Room 1003
100 Washington Square East
This event will recur Every Day until Apr. 12, 2019
Jeff Schneider (Logan/Kirshenbaum Labs, Sackler SoM/Chemistry, NYU)
"Design of Peptoid-peptide Macrocycles to Inhibit the β-catenin TCF Interaction in Prostate Cancer"
Wnt/β-catenin signaling has been shown to play an important role in multiple forms of cancer but currently has no approved targeted therapies. We used computational tools to develop a novel inhibitor that targets a critical interaction in the Wnt pathway.
Dr. Damian Ekiert (Ekiert Lab, Sackler SoM, NYU)
"Building a Wall: How the Bacterial Outer Membrane is Assembled and Maintained"
The bacterial outer membrane is a critical barrier that protects the cell from antibiotics. The Ekiert Lab studies a ubiquitous family of lipid transporters called MCE, which are important for outer membrane integrity but whose precise molecular function is not well understood.