Neuroplasticity and Disease
SAME AS NEURL-GA 1101.
An introductory multidisciplinary course in Neuroplasticity is offered which covers the basic principles of biology, anatomy, endocrinology and pharmacology in typical and atypical human physiology in health and disease. All cells in the brain will be studied including stem cells, neurons, astrocytes, microglia and pericytes. Human diseases will be organized in clusters of Global Insults (e.g. tumors and stokes); Genetic Diseases (e.g. Huntington’s and Down syndrome); Region Specific diseases (e.g. Parkinson’s and oppositional defiant disorder); Chemical associated diseases (e.g. FAS and depression) and Treatments (e.g. opiates and amphetamines) These topics will be discussed in class on how they impact cytoskeletal and spine dynamics, neuronal migration, degeneration, memory, and aggression. Special attention is paid to the cellular actions of neurotransmitters, stress hormones, trophic factors, marijuana and opiates. Discussion of current literature and preparation of a term paper provide an in depth coverage of the subject of neuroplasticity and how it relates to human diseases.