Nadrian C. Seeman

Nadrian C. Seeman

Margaret and Herman Sokol Professor of Chemistry;
B.S. University of Chicago; Ph.D. University of Pittsburgh; Postdoctoral research at Columbia University and MIT

Email:

Research Interests:

DNA Nanotechnology, Macromolecular Design and Topology, Biophysical Chemistry of Recombinational Intermediates, DNA-Based Computation, and Crystallography

Affiliations:

American Crystallographic Association American Association for the Advancement of Science Biophysical Society New York Academy of Sciences American Chemical Society Sigma Xi American Society for Biochemistry and Molecular Biology Materials Research Society Pittsburgh Diffraction Society

Fellowships/Honors:

Damon Runyon Fellow (1972-3), NIH Postdoctoral Fellow (1973-1976), Sidhu Award for RNA crystallography (1974), Basil O'Connor Fellow (1978-1981), NIH Research Career Development Award (1982-1987), Feynman Prize in Nanotechnology for the construction of DNA polyhedra (1995), Discover award in Emerging Technologies for DNA tinkertoys (1997), Honorary Distinguished Prof., Univ. Peruana Cayetano Heredia(1998-), Elected AAAS Fellow(1998), Margaret and Herman Sokol Award in the Sciences, for founding DNA nanotechnology (1999), Margaret and Herman Sokol Chair in Chemistry, New York University (2001-), Tulip Award in DNA-Based Computation (2004), Elected Fellow of Royal Society of Chemistry (2005), NIH MERIT Award (2005), Nanotech Briefs Nano50 Innovator Award for DNA nanotechnology (2005), World Technology Network Biotechnology Award (2005), Festschrift Volume, Nanotechnology: Science and Computation, (J.Chen, N.Jonoska, G.Rozenberg, Eds), Springer-Verlag, Berlin (2006)

Selected Works:

S. Liao and N.C. Seeman, Translation of DNA Signals into Polymer Assembly Instructions, Science 306, 2072-2074 (2004).

N.C. Seeman, From Genes to Machines: DNA Nanomechanical Devices, Trends in Biochemical Sciences 30, 119-235 (2005).

N.C. Seeman and P.S. Lukeman, Nucleic Acid Nanostructures, Reports on Progress in Physics 68, 237-270 (2005).

F. Mathieu, S. Liao, C. Mao, J. Kopatsch, T. Wang, and N.C. Seeman, Six-Helix Bundles Designed from DNA, NanoLetters 5, 661-665 (2005).

N.C. Seeman, The Challenge of Structural Control on the Nanoscale: Bottom-Up Self-Assembly of Nucleic Acids in 3D, Int. J. Nanotech. 2, 348-370 (2005)

M. Endo, N.C. Seeman and T. Majima, DNA Tube Structures Controlled by a Four-Way-Branched DNA Connector, Angew. Chemie, Int. Ed. 44 6074-6077 (2005).

Y.Y. Pinto, N.C. Seeman, K. Musier-Forsyth, T.A. Taton & R. A. Kiehl, Sequence-Encoded Self-Assembly of Multiple-Nanocomponent Arrays by 2D DNA Scaffolding, NanoLetters 5, 2399-2402 (2005).

W.B. Sherman & N.C. Seeman, Design of Low-Stress Nucleic Acid Nanotubes, Bioiphys. J., 90, 4546-4557 (2006).

J. Zheng, P.E. Constantinou, C. Micheel, A.P. Alivisatos, R.A. Kiehl & N.C. Seeman, 2D Nanoparticle Arrays Show the Organizational Power of
Robust DNA Motifs, NanoLetters 6, 1502-1504 (2006).

A.V. Garibotti, S.M. Knudsen, A.D. Ellington & N.C. Seeman, Functional DNAzymes Organized into 2D Arrays, NanoLetters 6, 1505-1507 (2006).

P. Constantinou, T. Wang, J. Kopatsch, L.B. Israel, X. Zhang, B. Ding, W.B. Sherman, X. Wang, J. Zheng, R. Sha, N. C. Seeman, Double Cohesion in Structural DNA Nanotechnology, Organic and Biomolecular Chemistry 4, 3414-3418 (2006).

J.J. Birac, W.B. Sherman, J. Kopatsch, P.E. Constantinou and N.C. Seeman, GIDEON, A Program for Design in Structural DNA Nanotechnology, J. Mol. Graphics & Modeling 25, 470-480 (2006).

G. Wu & N.C. Seeman, A Method of Multiplying with DNA, Natural Computing 5, 427-441, (2006).

B. Ding & N.C. Seeman, Operation of a DNA Robot Arm Inserted Into a 2D DNA Crystalline Substrate, Science 314, 1583-1585 (2006).

H. Zhong & N.C. Seeman, RNA Used to Control a DNA Rotary Machine, NanoLetters 6, 2899-2903 (2006).

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