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John Spencer EvansPrinter Friendly Printer Friendly

Professor of Chemistry
B.S. Northwestern University; Ph.D. California Institute of Technology

Email:

Research Interests:

Biomimetic or "Nature"-based materials, macromolecule-interfacial interactions, biomineralization, nuclear magnetic resonance spectroscopy, protein structure determination, mass spectrometry, computational chemistry

Affiliations:

New York Academy of Sciences (Biophysics), Biophysical Society, American Chemical Society, Protein Society

Fellowships/Honors:

Whitaker Foundation Bioengineering Young Investigator Award (1994); National Science Foundation CAREER Award (1995); US Army Research Office Young Investigator Award (1998)

Selected Works:

Amos, F.F., Ndao, M., Evans, J.S. (2010) Intrinsic disorder and evidence of mineralization activity within the N-terminal region of ACCBP,  a biomineralization protein that is homologous to the acetylcholine binding protein family.  Biomacromolecules, in press.

So, C., Kulp, J.K., III, Oren, E., Zareie, H., Tamerler, C., Evans, J.S., Sarikaya, M. (2009) Molecular recognition and supramolecular self-assembly of a genetically engineered gold binding peptide on Au(111).  ACS Nano 3, 1525-1531.

Delak, K., Collino, S., Evans, J.S. (2009) Polyelectrolyte domains and intrinsic disorder within the prismatic Asprich protein family.  Biochemistry, 48, 3669-3677.

Delak, K., Harcup, C., Lakshminarayanan, R., Zhi, S.,  Fan, Y.,  Moradian-Oldak, J., Evans, J.S. (2009) The tooth enamel protein, porcine amelogenin, is an intrinsically disordered protein with an extended molecular configuration in the monomeric form.  Biochemistry, 48, 2272-2281.

Amos, F.F., Evans, J.S. (2009) AP7, a partially disordered pseudo C-RING protein, is capable of forming stabilized aragonite in vitro.  Biochemistry 48, 1332-1339.

Delak, K, Giocondi, J, Orme, C, Evans, JS (2008) Modulation of crystal growth by the terminal sequences of the prismatic associated Asprich protein. Crystal Growth and Design 8:4481-4486.

Evans, JS, (2008) “Tuning in” to mollusk shell nacre- and prismatic-associated protein terminal sequences.  Implications for biomineralization and the construction of high performance inorganic-organic composites.  Chem. Rev.108:  4455-4462.

Hnilova, M., Oren, E.E., Seker, U.O.S., Wilson, B.R., Collino, S., Evans, J.S., Tamerler, C., Sarikaya, M.  (2008) Effect of molecular conformations on adsorption behavior of gold binding peptides.  Langmuir, 24: 12440-12445.

Collino, S., Evans, JS, (2008) The molecular specifications of a mineral modulation sequence derived from the aragonite-promoting protein, n16.  Biomacromolecules, 9, 1909-1918.

Collino, S., Kim, I.W., Evans, JS (2008) Identification and structural characterization of an unusual RING-like sequence within an extracellular biomineralization protein,  AP7.  Biochemistry 47:  3745-3755.

Evans, JS, Samudrala, R, Walsh, T, Oren, EE, Tamerler, C (2008)  Molecular design of inorganic - binding polypeptides.  MRS Bulletin, 33:  8-14.

Kim, IW, Giocondi, JL, Orme, C, Collino, S, Evans, JS (2008) Morphological transformation of calcite crystal growth by prismatic “acidic” polypeptide sequences.  Crystal Growth and Design, 8:  1154-1160.

Collino, S, Evans, JS, Molecular characterization of a mineral modification subdomain of the aragonite associated protein, AP24.  Biomacromolecules, in press.

Kulp, JL III, Minamisawa, T, Shiba, K, Evans, JS (2007) Conformational properties of an artificial protein that regulates the nucleation of inorganic and organic crystals.  Langmuir,in press.

Kim, IW, Darragh, MR, Orme, C, Evans, JS (2006)  Molecular “tuning” of crystal growth by nacre-associated polypeptides. Crystal Growth and Design, 5: 5-10.

Collino, S, Kim, IW, Evans, JS, (2006) Identification of an “acidic” C-terminal mineral modification sequence from the mollusk shell protein, Asprich. Crystal Growth and Design, 6: 839-842.

Kim, IW, Collino, S, Morse, DE, Evans, JS (2006) A crystal modulating protein from molluscan nacre that limits the growth of calcite in vitro.  Crystal Growth and Design, 6: 1078-1082.

Kulp, JL, Shiba, K, Evans, JS. (2005) Probing the conformational features of a phage display polypeptide sequence directed against single wall carbon nanohorn surfaces.  Langmuir, 21:  11907-11914.

Kim, IW, Morse, DE, Evans, JS (2004) Molecular characterization of the 30-AA N-terminal mineral interaction domain of the biomineralization protein AP7.  Langmuir 20: 11664-11673.

Kase, D, Kulp, JL III, Yudasaka, M, Evans, JS, Iijima, S, Shiba, K (2004) Affinity selection of peptide phage libraries against single-wall carbon nanohorns identify a peptide aptamer with pH and temperature dependent conformational variability.  Langmuir 20:  3989-3991.

Kim, IW, DiMasi, E, Evans, JS, (2004) Identification of mineral modulation sequences within the nacre-associated oyster shell protein, n16.  Crystal Growth and Design 4:  1113 - 1118.

Kulp, JL III, Sarikaya, M, Evans, JS (2004) Molecular characterization of a prokaryotic polypeptide sequence that catalyzes Au crystal formation.  Journal of Materials Chemistry 14: 2325-2332.

Wustman, BA, Morse, DE, Evans, JS (2004) Structural characterization of the N-terminal mineral modification domains from the molluscan crystal-modulating biomineralization proteins, AP7 and AP24.  Biopolymers 74: 363-376.

Michenfelder, M, Fu, G, Lawrence, C, Weaver, JC, Wustman, BA, Taranto, L, Evans, JS (2003) Characterization of two molluscan crystal-modulating biomineralization proteins and identification of putative mineral binding domains.  Biopolymers 70: 522-533; errata 73: 522.

Evans, JS (2003) Apples and oranges:  Comparing the structural aspects of biomineral- and ice-interaction proteins.   Current Opinion in Colloid and Interface Science 8:  48-54.

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