Carlos Carmona-Fontaine

Assistant Professor of Biology


Ph.D. University College London, UK, Cell and Developmental Biology 2010

Bsc, Pontificia Universidad Católica de Chile, Chile

Areas of Research/Interest

Multicellular organization in health and disease; Cell biology. Cancer and developmental biology; Social behaviors in cells


K99 NIH Pathway to Independence Award

Beddington Medal Recipient from the BSDB

Boehringer Ingelheim Fonds PhD Fellowship


L-2-Hydroxyglutarate production arises from noncanonical enzyme function at acidic pH.
Nat Chem Biol (2017 May) PMID: 28263965
Intlekofer AM, Wang B, Liu H, Shah H, Carmona-Fontaine C, Rustenburg AS, Salah S, Gunner MR, Chodera JD, Cross JR, Thompson CB

Metabolic origins of spatial organization in the tumor microenvironment.
Proc Natl Acad Sci U S A (2017 Mar 14) PMC5358370 free full-text archive
Carmona-Fontaine C, Deforet M, Akkari L, Thompson CB, Joyce JA, Xavier JB

Delamination of neural crest cells requires transient and reversible Wnt inhibition mediated by Dact1/2.
Development (2016 Jun 15) PMC4920176 free full-text archive
Rabadan MA, Herrera A, Fanlo L, Usieto S, Carmona-Fontaine C, Barriga EH, Mayor R, Pons S, Marti E

Extracellular matrix couples the convergence movements of mesoderm and neural plate during the early stages of neurulation.
Dev Dyn (2016 May) PMID: 26933766
Araya C, Carmona-Fontaine C, Clarke JD

Directional collective cell migration emerges as a property of cell interactions.
PLoS One (2014) PMC4152153 free full-text archive
Woods ML, Carmona-Fontaine C, Barnes CP, Couzin ID, Mayor R, Page KM

Mesoderm is required for coordinated cell movements within zebrafish neural plate in vivo.
Neural Dev (2014 Apr 23) PMC4022452 free full-text archive
Araya C, Tawk M, Girdler GC, Costa M, Carmona-Fontaine C, Clarke JD

Hyperswarming adaptations in a bacterium improve collective motility without enhancing single cell motility.
Soft Matter (2014 Apr 14) PMC3955847 free full-text archive
Deforet M, van Ditmarsch D, Carmona-Fontaine C, Xavier JB

Tumour-stromal interactions generate emergent persistence in collective cancer cell migration.
Interface Focus (2013 Aug 06) PMC3915836 free full-text archive
Chang WK, Carmona-Fontaine C, Xavier JB

Emergence of spatial structure in the tumor microenvironment due to the Warburg effect.
Proc Natl Acad Sci U S A (2013 Nov 26) PMC3845113 free full-text archive
Carmona-Fontaine C, Bucci V, Akkari L, Deforet M, Joyce JA, Xavier JB

Altruistic cell death and collective drug resistance.
Mol Syst Biol (2012) PMC3531905 free full-text archive
Carmona-Fontaine C, Xavier JB

Complement fragment C3a controls mutual cell attraction during collective cell migration.
Dev Cell (2011 Dec 13) PMC3272547 free full-text archive
Carmona-Fontaine C, Theveneau E, Tzekou A, Tada M, Woods M, Page KM, Parsons M, Lambris JD, Mayor R

Keeping in touch with contact inhibition of locomotion.
Trends Cell Biol (2010 Jun) PMC2927909 free full-text archive
Mayor R, Carmona-Fontaine C

Directional cell migration in vivo: Wnt at the crest.
Cell Adh Migr (2008 Oct-Dec) PMC2633683 free full-text archive
Carmona-Fontaine C, Matthews H, Mayor R

Contact inhibition of locomotion in vivo controls neural crest directional migration.
Nature (2008 Dec 18) PMC2635562 free full-text archive
Carmona-Fontaine C, Matthews HK, Kuriyama S, Moreno M, Dunn GA, Parsons M, Stern CD, Mayor R

Directional migration of neural crest cells in vivo is regulated by Syndecan-4/Rac1 and non-canonical Wnt signaling/RhoA.
Development (2008 May) PMID: 18403410
Matthews HK, Marchant L, Carmona-Fontaine C, Kuriyama S, Larrain J, Holt MR, Parsons M, Mayor R

Neural crests are actively precluded from the anterior neural fold by a novel inhibitory mechanism dependent on Dickkopf1 secreted by the prechordal mesoderm.
Dev Biol (2007 Sep 15) PMID: 17669393
Carmona-Fontaine C, Acuna G, Ellwanger K, Niehrs C, Mayor R

Chronic stress decreases the expression of sympathetic markers in the pineal gland and increases plasma melatonin concentration in rats.
J Neurochem (2006 Jun) PMID: 16539651
Dagnino-Subiabre A, Orellana JA, Carmona-Fontaine C, Montiel J, Diaz-Veliz G, Seron-Ferre M, Wyneken U, Concha ML, Aboitiz F

Chronic stress impairs acoustic conditioning more than visual conditioning in rats: morphological and behavioural evidence.
Neuroscience (2005) PMID: 16165300
Dagnino-Subiabre A, Terreros G, Carmona-Fontaine C, Zepeda R, Orellana JA, Diaz-Veliz G, Mora S, Aboitiz F

Do discreteness and rivalry coexist in illusory motion reversals?
Vision Res (2006 Mar) PMID: 16139861
Rojas D, Carmona-Fontaine C, Lopez-Calderon J, Aboitiz F

Genetic network during neural crest induction: from cell specification to cell survival.
Semin Cell Dev Biol (2005 Dec) PMID: 16084743
Steventon B, Carmona-Fontaine C, Mayor R